Cancer: The Metabolic Disease Unravelled (The Real Truth About Cancer) Paperback – September 8, 2018

Mark’s book was so compelling that I read it twice. He also influenced me to include oranges and pectin in my diet. (Still not a fan of orange juice for glycemic reasons-- my preference is the whole fruit.)I am also considering preparing a daily cocktail of sodium bicarbonate (baking soda) and water to raise my blood pH since acidic conditions seem to favor the disease processes.Mark has compiled a masterpiece of research studies. For decades cancer has been pigeonholed into a hereditary genetic envelope. Mark makes a strong case that cancer results from aberrations of metabolic processes in the cellular environment.These aberrations cause malevolent expressions of some genes. By the same mechanism, an optimal or healthful environment may repress these tragic gene expressions.Mark hypothesizes that cancer is a disease of the mitochondria and the tumor microenvironment. He believes that cancer results from cell injury. This injury then gets compounded in a toxic microenvironment.Any number of factors can cause cell injuries such as trauma, chemicals, nutritional deficiencies, viruses, bacteria, radiation, or cell anomalies.Three common factors that cause extensive damage to the tissue area surrounding tumors are 1) acidic or low pH, 2) lack of adequate oxygen, and 3) reduced CO2 levels.When suboptimal conditions like these are present, the Glycolysis/Krebs Tricarboxylic Cycle/Oxidative phosphorylation Cycle aborts in favor of the first stage, Glycolysis.A cell metabolism using only Glycolysis for energy produces an abundance of lactic acid and less energy than the full Oxidative phosphorylationThe excess of lactic acid further lowers the pH of the toxic microenvironment producing a snowballing or cascading effect.The medical profession and the public have generally ignored diet as it relates to health and cancer growth. For the last forty years, nutritional guidance is that foods high in carbohydrates were ideal for human health and longevity and that saturated fats were just plain unhealthy.Mark has pointed to numerous experiments that have shown that it’s not the saturated fats (coconut oil, beef fat, lard) but rather the unsaturated oils that fuel tumor growth (corn oil, soybean oil, safflower oil).He has shown that natural medicines like oranges, coconut oil, sodium bicarbonate, and aspirin are game-changers. Alternate natural therapies and wound care need to incorporate these ingredients; instead of the corrosive chemo and radiation that compound tissue damage.Mark believes that the CO2 levels in the blood and the body have a strong correlation to health. CO2 is typically in abundance in successful oxidative phosphorylation since CO2 is one of the byproducts of the Glycolysis/Krebs Tricarboxylic Cycle/Oxidative Phosphorylation Cycle.Mark’s over-exuberance, however, include some dubious findings. Some of these seem more anecdotal than clinical.Two examples stand out:1) While expounding on the virtues of Sodium bicarbonate. Mark included the following bullet point: “Sodium bicarbonate significantly increases punches landed during 4 rounds of boxing.”(Who cares and how can this be measured reproducibly—way too many variables.)2) While enumerating the virtues of Lauric acid (which I applaud), I found this quote: “Lauric acid enhances absorption of medication through shed snake skin.”(Who outside the reptile community cares—no sick cobras to speak of.)Some of the conclusions may be in research papers but not relevant or insightful to the overall theme of this work.Also, his strong advocacy for CO2 leads him to some bizarre comments on the global environmental crisis concerning greenhouse gases.To paraphrase: Mark believes so much in CO2 that any elevation in CO2 is both beneficial to man and plants.This belief seems to ignore the apparent effect of global warming by trapping heat and melting of the polar ice caps with the concurrent rise in sea level and massive weather turbulence and instability.(If he lived in a coastal region, he would literally be all wet.)Before reading this book, I assumed that metastasis means that the cancer cells are rapidly dividing. Mark cast doubts on that conclusion by showing experiments demonstrating an influx of stem cells get caught in the toxic microenvironment and succumb to the metastasis by mutating.Some of the fascinating studies cited include the cloning of mice from tumor cell DNA, frog egg tumor transplants, and cell cytoplasm-swapped ‘cybrids’.It is interesting how cancer cells utilize vast amounts of glucose at first but then later switch to catabolizing muscle tissue, which results in the awful wasting away of muscle tissue called cachexia. This is the emaciation we see in the final stages.Wouldn’t it make sense to switch the patient’s diet to a diet higher in fat? Specifically, one infused with more medium-chained triglycerides like coconut oil or MCTs since the body prefers these molecules for energy?Could it possibly prevent the terrible wasting of vital muscle tissue and give the patient a better chance at recovery?Clearly, our high carbohydrate diet doesn’t make sense for staying healthy.Mark has a thought-provoking excellent read.

This is the second book I've read by Mark Sloan. He does tons of research, indicated by the fact that over half the book is an ENORMOUS list of verified references that support all the claims in the book. Anyone who has cancer, or knows someone who does, needs to read this book. It not only explains what cancer is, how it develops and spreads, and how to safely and cheaply cure it. Don't submit to the corrupt medical industry's outdated and barbaric cancer treatments that do serious damage and aren't a guaranty for survival. Cancer, as well as all other diseases, are merely symptoms of the only true disease, the disruption of cellular metabolism.

This makes so much sense. I'm glad a friend recommended it to me. My question: In the end he references a third book that will provide nutritional protocol. But I can't seem to find it anywhere. Does it exist?

The book is well researched and dispels the theory that cancer is attacking and traveling in our bodies. I’m treating my breast cancer as a metabolic deficiency and I have not had my breast removed for a coffee bean sized tumor. I did take an Aromatase inhibitor 22 months to stop the estrogen receptor tumor growth while I increased consumption of oranges, raspberries, green tea, olive oil and coconut oil. Thank you for supporting my choice to refuse surgery and invasive treatment.

I’m unsure how this bk found me, but glad it did & it was so good I got 3 other Sloan bks! Mark, thank u 4collecting 150 yrs of research in 1 place 4us &showing how we already have a metabolic solution 2cancer (& the basis of every chronic disease!) I only wish I’d known what I now do, 6.5 yrs ago when my Sweetie was handed a death-sentence for leukemia. I guess lk u Mark I’ve bn reading 2find answers 4why a 72yo healthy runner who ate well got cancer. Alot 2ponder here. Unlk Mark, my mtr is still alive despite 5 different cancers &multi other diseases in her 99 yrs, all trusted 2con-ventional treatments. Ever an idealist, I keep thinking my research & knowledge may still serve her. The bk is 150 pp text/150 pp refs! Mark has an ease w making medicalese &bio- chem EZ 2grasp. Ray Peat fans will b pleased that Ray has 11 index citations thruout the bk. In a YouTube Strong Sistas interview of Ray he refers 2a PUFA bk “due out soon” (so I wrote it was likely this bk 4those asking!), as I’d seen Peat acknowledged by this author at the start of his 1st bk (Cancer Industry) 4his guidance & generosity. Of 4 Sloan bks the 2 re cancer r favs. I hope 2c bk 3 in this series soon, Mark! Until then, get this bk, everyone. It’s refreshing 2come across an author bold enuf 2counter sacred cows in the cancer king-dom esp nt having2 work2 comprehend It all.

I heard this book is so informative. I am reading it to gain knowledge for myself, but also for a family member with cancer now. I have not received it yet, but heard it was a great read.